H3B-6527
| CAS No. | 1702259-66-2 | Cat. No. | BCP17555 |
| Name | H3B-6527 | ||
| Synonyms | H3B 6527;H3B6527;Eisai;H3 Biomedicine; | ||
| Formula | C29H34Cl2N8O4 | M. Wt | 629.54 |
| Description | H3B-6527 is a potent and orally active FGFR4 inhibitor with potential antineoplastic activity. Upon administration, H3B-6527 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FGFR | ||
Structure
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