Trofinetide

  • Chemical Properties
CAS No. 853400-76-7 Cat. No. BCP17581
Name Trofinetide
Synonyms NNZ-2566; NNZ 2566; NNZ2566;
Formula C13H21N3O6 M. Wt 315.32
  • Biological Activity
Description Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome.
Pathways Others Pathway 
Targets Others 

Structure

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