KS 176

  • Chemical Properties
CAS No. 1253452-78-6 Cat. No. BCP17744
Name KS 176
Synonyms KS-176;KS176;
Formula C22H19N3O5 M. Wt 405.4
  • Biological Activity
Description KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
Pathways Ion Channel/Membrane Transporter 
Targets BCRP 

Structure

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