SB366791

  • Chemical Properties
CAS No. 472981-92-3 Cat. No. BCP17766
Name SB366791
Synonyms SB-366791;SB 366791;
Formula C16H14ClNO2 M. Wt 287.74
  • Biological Activity
Description SB-366791 produced a concentration-dependent inhibition of the response to capsaicin with an apparent pKb of 7.74±0.08. Schild analysis indicated a competitive mechanism of action with a pA2 of 7.71.SB-366791 showed a concentration-dependent potentiation of pH 5-induced 45Ca2+uptake in CHO cells expressing rat TRPV1 but not in untransfected cells.
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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