L778123 hydrochloride
| CAS No. | 253863-00-2 | Cat. No. | BCP17750 |
| Name | L778123 hydrochloride | ||
| Synonyms | L-778123 hydrochloride;L 778123 hydrochloride; | ||
| Formula | C22H21Cl2N5O | M. Wt | 442.34 |
| Description | in vitro: L-778123 can completely inhibit Ki-Ras prenylation. L-778123 as a farnesyltransferase inhibitor can have a good cytotoxic activity as a classic anti-cancer agent. in vivo: In the dog model, L-778123 inhibits HDJ2 prenylation and produces measurable, albeit slight (5%), levels of unprenylated. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FTase | ||
Structure
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