Omapatrilat

  • Chemical Properties
CAS No. 167305-00-2 Cat. No. BCP17901
Name Omapatrilat
Synonyms BMS 186716;BMS-186716;BMS186716;
Formula C19H24N2O4S2 M. Wt 408.53
  • Biological Activity
Description Omapatrilat is a novel antihypertensive agent that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme. NEP inhibition results in elevated natriuretic peptide levels, promoting natriuresis, diuresis, vasodilation, and reductions in preload and ventricular remodeling. The drug was promoted for possible uses in congestive heart failure.
Pathways Protease/Metabolic Enzyme Hormone Pathay 
Targets RAAS/ACE 

Structure

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