Epetraborole

  • Chemical Properties
CAS No. 1093643-37-8 Cat. No. BCP18025
Name Epetraborole
Synonyms AN-3365;AN 3365;GSK2251052;
Formula C11H16BNO4 M. Wt 237.06
  • Biological Activity
Description Epetraborole, also known as GSK2251052 and AN3365, is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. GSK2251052 is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of >32 μg/ml.
Pathways Others Pathway 
Targets Others 

Structure

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