AAL-993

  • Chemical Properties
CAS No. 269390-77-4 Cat. No. BCP18097
Name AAL-993
Synonyms AAL993;AAL 993;ZK260253;
Formula C20H16F3N3O M. Wt 371.36
  • Biological Activity
Description AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets VEGFR 

Structure

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