AAL-993
CAS No. | 269390-77-4 | Cat. No. | BCP18097 |
Name | AAL-993 | ||
Synonyms | AAL993;AAL 993;ZK260253; | ||
Formula | C20H16F3N3O | M. Wt | 371.36 |
Description | AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM). | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | VEGFR |
Structure
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