Tenovin6 Hydrochloride
| CAS No. | 1011301-29-3 | Cat. No. | BCP18122 |
| Name | Tenovin6 Hydrochloride | ||
| Synonyms | Tenovin-6 Hydrochloride;Tenovin 6 Hydrochloride; | ||
| Formula | C25H34N4O2S.HCl | M. Wt | 491.09 |
| Description | Inhibition of the Sirtuin class of protein deacetylases with activation of p53 function is associated with the pro-apoptotic effects of Tnv-6 in many tumors. Tnv-6 causes non-genotoxic cytotoxicity, without adversely affecting human clonogenic hematopoietic progenitors in vitro, or murine hematopoiesis. Mechanistically, exposure of CLL cells to Tnv-6 did not induce cellular apoptosis or p53-pathway activity. Transcriptomic profiling identified a gene program influenced by Tnv-6 that included autophagy-lysosomal pathway genes. | ||
| Pathways | Cell Cycle/DNA Damage Apoptosis Pathway Epigenetics | ||
| Targets | Sirtuin HDAC p53 | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.