PLX7904
| CAS No. | 1393465-84-3 | Cat. No. | BCP18248 |
| Name | PLX7904 | ||
| Synonyms | PLX-7904;PLX 7904;PB04; | ||
| Formula | C24H22F2N6O3S | M. Wt | 512.53 |
| Description | PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. PB04 is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. | ||
| Pathways | MAPK Pathway | ||
| Targets | Raf | ||
Structure
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