Bimolane

  • Chemical Properties
CAS No. 74550-97-3 Cat. No. BCP18269
Name Bimolane
Synonyms AT-1727;AT 1727;AT1727; CCRIS 7574; CCRIS7574; CCRIS-7574;
Formula C20H32N6O6 M. Wt 452.5
  • Biological Activity
Description Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors.
Pathways Cell Cycle/DNA Damage 
Targets Topoisomerase 

Structure

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