Ropivacaine
| CAS No. | 84057-95-4 | Cat. No. | BCP18319 |
| Name | Ropivacaine | ||
| Synonyms | LEA 103; LEA-103; LEA103; | ||
| Formula | C17H26N2O | M. Wt | 274.4 |
| Description | Ropivacain is a potent sodium channel blocker and acts as a local anesthetic agent. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is used for the research of regional anesthesia and neuropathic pain management. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel Sodium Channel | ||
Structure
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