Fosbretabulin
CAS No. | 222030-63-9 | Cat. No. | BCP18350 |
Name | Fosbretabulin | ||
Synonyms | CA4DP; Combretastatin A-4; | ||
Formula | C18H21O8P | M. Wt | 396.33 |
Description | Fosbretabulin is a natural cis-stilbene which interferes with the cellular tubulin dynamics and which selectively destroys tumour blood vessels. Its pharmacological shortcomings such as insufficient chemical stability, water solubility, and cytotoxicity can be remedied by employing its imidazole derivatives. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | Microtubule |
Structure
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