Fosbretabulin

  • Chemical Properties
CAS No. 222030-63-9 Cat. No. BCP18350
Name Fosbretabulin
Synonyms CA4DP; Combretastatin A-4;
Formula C18H21O8P M. Wt 396.33
  • Biological Activity
Description Fosbretabulin is a natural cis-stilbene which interferes with the cellular tubulin dynamics and which selectively destroys tumour blood vessels. Its pharmacological shortcomings such as insufficient chemical stability, water solubility, and cytotoxicity can be remedied by employing its imidazole derivatives.
Pathways Cell Cycle/DNA Damage 
Targets Microtubule 

Structure

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