DEL-22379
| CAS No. | 181223-80-3 | Cat. No. | BCP18363 |
| Name | DEL-22379 | ||
| Synonyms | DEL 22379;DEL22379; | ||
| Formula | C26H28N4O3 | M. Wt | 444.53 |
| Description | DEL-22379 is a potent and selective ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization without affecting ERK phosphorylation, forestalls tumorigenesis driven by RAS-ERK pathway oncogenes. Nearly 50% of human malignancies exhibit unregulated RAS-ERK signaling; inhibiting it is a valid strategy for antineoplastic intervention. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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