THZ2
| CAS No. | 1604810-84-5 | Cat. No. | BCP24675 |
| Name | THZ2 | ||
| Synonyms | THZ 2; THZ-2; | ||
| Formula | C31H28ClN7O2 | M. Wt | 566.05 |
| Description | THZ2, an analog of THZ1, with the potential to treat Triple-negative breast cancer (TNBC), it is a potent and selective CDK7 inhibitor which overcomes the instability of THZ1 in vivo. IC50: CDK7= 13.9 nM; TNBC cells= 10 nM | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | CDK | ||
Structure
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