Phorbol 12-Myristate 13-Acetate

  • Chemical Properties
CAS No. 16561-29-8 Cat. No. BCP18478
Name Phorbol 12-Myristate 13-Acetate
Synonyms PMA;
Formula C36H56O8 M. Wt 616.83
  • Biological Activity
Description Phorbol 12-myristate 13-acetate (PMA) is a PKC-activating phorbol ester, increases the intracellular Ca2+ concentration ([Ca2+]i) in a dose-dependent manner, with an EC50 of 11.7 nM.
Pathways TGF beta/Smad  Epigenetics 
Targets PKC 

Structure

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