Entacapone
CAS No. | 116314-67-1 | Cat. No. | BCP18653 |
Name | Entacapone | ||
Synonyms | 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide; | ||
Formula | C14H15N3O5 | M. Wt | 305.29 |
Description | Entacapone is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa. Entacapone has been associated with a low rate of serum enzyme elevations during treatment, but has yet to be implicated in cases of clinically apparent acute liver injury with jaundice. | ||
Pathways | Neuro Signaling Pathway | ||
Targets | COMT |
Structure
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