TMP195
| CAS No. | 1314891-22-9 | Cat. No. | BCP24720 |
| Name | TMP195 | ||
| Synonyms | TMP-195; TMP 195;TFMO 2; | ||
| Formula | C23H19F3N4O3 | M. Wt | 456.42 |
| Description | TMP195 is a potent and selective class IIa HDAC inhibitor with IC50s of 59 nM, 60 nM, 26 nM and 15 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively. TMP195 can reprogram monocytes and macrophages in the tumor into cells able to sustain a robust CD8 T cell-mediated anti-tumoral immune response. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | HDAC | ||
Structure
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