PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid)

  • Chemical Properties
CAS No. 1210344-83-4 Cat. No. BCP18768
Name PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid)
Synonyms PF 04971729;PF04971729;MK-8835;MK 8835;MK8835; PF-04971729-00; Ertugliflozin;
Formula C22H25ClO7 M. Wt 436.88
  • Biological Activity
Description Ertugliflozin, also known as also known as PF-04971729, is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. clinical study showed that Ertugliflozin (1-25 mg/day) improved glycaemic control, body weight and blood pressure in patients with T2DM suboptimally controlled on metformin, and was well tolerated.
Pathways Ion Channel/Membrane Transporter GPCR/G Protein 
Targets SGLT 

Structure

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