埃格列净 共晶
| CAS号 | 1210344-83-4 | 货号 | BCP18768 |
| 中文名 | 埃格列净 共晶 | ||
| 英文名 | PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid) | ||
| 中文别名 | |||
| 英文别名 | PF 04971729;PF04971729;MK-8835;MK 8835;MK8835; PF-04971729-00; Ertugliflozin; | ||
| 分子式 | C22H25ClO7 | 分子量 | 436.88 |
| 生物活性 | Ertugliflozin, also known as also known as PF-04971729, is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. clinical study showed that Ertugliflozin (1-25 mg/day) improved glycaemic control, body weight and blood pressure in patients with T2DM suboptimally controlled on metformin, and was well tolerated. | ||
| 信号通路 | Ion Channel/Membrane Transporter GPCR/G Protein | ||
| 靶 点 | SGLT | ||
结构式
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