GSK369796 Dihydrochloride
| CAS No. | 1010411-21-8 | Cat. No. | BCP18835 |
| Name | GSK369796 Dihydrochloride | ||
| Synonyms | GSK 369796; GSK-369796; GSK369796; | ||
| Formula | C20H24Cl3N3O | M. Wt | 428.78 |
| Description | GSK369796 Dihydrochloride is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.GSK369796 is an anti-malaria drug candidate. GSK369796 was rationally designed based on chemical, toxicological, pharmacokinetic, and pharmacodynamic considerations and was selected based on excellent activity against Plasmodium falciparum in vitro and rodent malaria parasites in vivo. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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