Halofuginone lactate

  • Chemical Properties
CAS No. 82186-71-8 Cat. No. BCP18878
Name Halofuginone lactate
Synonyms
Formula C19H23BrClN3O6 M. Wt 504.76
  • Biological Activity
Description Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
Pathways TGF beta/Smad  Wnt/Stem Cell 
Targets TGF β/Smad 

Structure

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