Vericiguat
CAS号 | 1350653-20-1 | 货号 | BCP18886 |
中文名 | Vericiguat | ||
英文名 | Vericiguat | ||
中文别名 | |||
英文别名 | BAY1021189; BAY 1021189; BAY-1021189; BAY10-21189; BAY-10-21189; BAY 10-21189; | ||
分子式 | C19H16F2N8O2 | 分子量 | 426.38 |
生物活性 | Vericiguat, also known as BAY1021189 or BAY10-21189, is a potent and orally active sGC stimulator (Soluble Guanylate Cyclase Stimulator). Direct stimulation of soluble guanylate cyclase (sGC) is emerging as a potential new approach for the treatment of renal disorders. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is implicated in the pathogenesis of chronic kidney disease (CKD). | ||
信号通路 | GPCR/G Protein | ||
靶 点 | Guanylate Cyclase |
结构式
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