BFH772
CAS No. | 890128-81-1 | Cat. No. | BCP18910 |
Name | BFH772 | ||
Synonyms | BFH-772;BFH 772; | ||
Formula | C23H16F3N3O3 | M. Wt | 439.39 |
Description | BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | VEGFR |
Structure
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