Semaglutide
| CAS No. | 910463-68-2 | Cat. No. | BCP24773 |
| Name | Semaglutide | ||
| Synonyms | OG217SC; NNC 0113-0217;Ozempic;NN 9535;NN9535;NN-9535; NNC 0113-0217; NNC-0113-0217; NNC0113-0217; | ||
| Formula | C187H291N45O59 | M. Wt | 4113.64 |
| Description | Semaglutide is a glucagon like peptide 1 (GLP-1) receptor peptidomimetic agonist. Structurally it is a modified analogue of glucagon-like peptide 1-(7-37) with amino acids at positions 8 and 34 replaced by α-aminobutyric acid and arginine respectively, and Lys26 is acylated with stearic diacid. Semaglutide has slightly lower GLP-1 receptor affinity than liraglutide, but this is compensated by an increased serum albumin affinity, which ensures improved resistance to metabolic degradation. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Glucagon Receptor | ||
Structure
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