BMS-906024
| CAS号 | 1401066-79-2 | 货号 | BCP18995 |
| 中文名 | BMS-906024 | ||
| 英文名 | BMS-906024 | ||
| 中文别名 | |||
| 英文别名 | BMS 906024;BMS906024;Osugacestat; | ||
| 分子式 | C26H26F6N4O3 | 分子量 | 556.5 |
| 生物活性 | BMS-906024 is a novel, potent Notch receptor inhibitor . Cancers have a tendency to relapse or to become resistant to treatments that once worked. A family of proteins called Notch is implicated in that resistance and in cancer progression more generally. BMS-906024 is in Phase I clinical trials, both alone and in combination with other agents. Patients with colon, lung, breast, and other cancers are receiving intravenous doses of the compound to determine its safety and optimum dose ranges. | ||
| 信号通路 | Wnt/Stem Cell | ||
| 靶 点 | Notch | ||
结构式
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