AZD0156
| CAS No. | 1821428-35-6 | Cat. No. | BCP18990 |
| Name | AZD0156 | ||
| Synonyms | AZD-0156;AZD 0156; | ||
| Formula | C26H31N5O3 | M. Wt | 461.56 |
| Description | AZD0156 is an oral, potent and selective ATM kinase inhibitor, inhibiting the kinase activity of ATM and ATM-mediated signaling, preventing DNA damage checkpoint activation, and disrupting DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells. | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | ATM/ATR | ||
Structure
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