GR 127935 hydrochloride

  • Chemical Properties
CAS No. 148642-42-6 Cat. No. BCP19014
Name GR 127935 hydrochloride
Synonyms GR-127935 hydrochloride;GR127935 hydrochloride;GR 127935; GR-127935; GR 127935 HCl; GR 127935;
Formula C29H32ClN5O3 M. Wt 534.05
  • Biological Activity
Description GR 127935 HCl is a potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). GR 127935 HCl displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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