醋酸组氨瑞林
| CAS号 | 220810-26-4 | 货号 | BCP19027 |
| 中文名 | 醋酸组氨瑞林 | ||
| 英文名 | Histrelin Acetate | ||
| 中文别名 | |||
| 英文别名 | Supprelin;Vantas; | ||
| 分子式 | C66H86N18O12 | 分子量 | 1323.52 |
| 生物活性 | Histrelin Acetate is the acetate salt form of histrelin, a long-acting, synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH) with potential anti-tumor activity. Upon administration, histrelin binds to and activates GnRH receptors; prolonged administration results in pituitary GnRH receptor desensitization and inhibition of follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion, leading to a significant decline in testosterone production in males and may inhibit androgen receptor-positive tumor progression; in females, prolonged administration results in decreased estradiol production. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | GnRH Receptor | ||
结构式
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