Auristatin E
| CAS No. | 160800-57-7 | Cat. No. | BCP24782 |
| Name | Auristatin E | ||
| Synonyms | |||
| Formula | C40H69N5O7 | M. Wt | 732.01 |
| Description | Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent that inhibits tubulin polymerization. Auristatin E-antibody conjugates have proven to be successful anticancer agents. | ||
| Pathways | Cell Cycle/DNA Damage Others Pathway | ||
| Targets | ADC Related Microtubule | ||
Structure
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