AZD-8931 Difumaric acid
| CAS号 | 1196531-39-1 | 货号 | BCP24789 |
| 中文名 | AZD-8931 Difumaric acid | ||
| 英文名 | AZD-8931 Difumaric acid | ||
| 中文别名 | |||
| 英文别名 | AZD 8931 Difumaric acid;AZD8931 Difumaric acid;Sapitinib Difumaric acid; | ||
| 分子式 | C31H33ClFN5O11 | 分子量 | 706.07 |
| 生物活性 | AZD-8931 is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. erbB kinase inhibitor AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| 靶 点 | EGFR HER2 | ||
结构式
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