IKK16
| CAS No. | 873225-46-8 | Cat. No. | BCP19060 |
| Name | IKK16 | ||
| Synonyms | IKK-16;IKK 16; | ||
| Formula | C28H29N5OS | M. Wt | 483.63 |
| Description | IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). KK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. | ||
| Pathways | Others Pathway NFκB | ||
| Targets | IκB/IKK LRRK2 | ||
Structure
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