NU 2058
CAS No. | 161058-83-9 | Cat. No. | BCP19068 |
Name | NU 2058 | ||
Synonyms | NU-2058;NU2058; | ||
Formula | C12H17N5O | M. Wt | 247.3 |
Description | NU2058 is a competitive inhibitor of CDK2 with respect to ATP (Ki value CDK2, 12 3 μM) that binds in the ATP binding pocket in a different orientation from other purine-based inhibitors, including olomoucine and roscovotine. NU2058 is the lead compound in a structure-based drug discovery program to develop more potent and selective CDK inhibitors. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | CDK |
Structure
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