NU 2058

  • Chemical Properties
CAS No. 161058-83-9 Cat. No. BCP19068
Name NU 2058
Synonyms NU-2058;NU2058;
Formula C12H17N5O M. Wt 247.3
  • Biological Activity
Description NU2058 is a competitive inhibitor of CDK2 with respect to ATP (Ki value CDK2, 12 3 μM) that binds in the ATP binding pocket in a different orientation from other purine-based inhibitors, including olomoucine and roscovotine. NU2058 is the lead compound in a structure-based drug discovery program to develop more potent and selective CDK inhibitors.
Pathways Cell Cycle/DNA Damage 
Targets CDK 

Structure

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