BAY-1082439
| CAS No. | 1375469-38-7 | Cat. No. | BCP19095 |
| Name | BAY-1082439 | ||
| Synonyms | BAY10-82439; BAY 10-82439; BAY-10-82439;BAY 1082439;BAY1082439; | ||
| Formula | C25H30N6O5 | M. Wt | 494.55 |
| Description | BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with potential antineoplastic activity. PI3K alpha/beta inhibitor BAY1082439 selectively inhibits both PI3K alpha, including mutated forms of PIK3CA, and PI3K beta in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K-expressing and/or PTEN-driven tumor cells. By specifically targeting class I PI3K alpha and beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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