VU0364770
| CAS No. | 61350-00-3 | Cat. No. | BCP19097 |
| Name | VU0364770 | ||
| Synonyms | VU-0364770;VU 0364770; | ||
| Formula | C12H9ClN2O | M. Wt | 232.67 |
| Description | VU0364770 is a potent and effective positive allosteric modulator of mGlu4. VU0346770 exhibits a potency of 1.1 ± 0.2 μM at human mGlu4 in the presence of an EC20 concentration of glutamate and shifts the glutamate concentration-response curve 31.4 ± 4.0-fold to the left. VU0364770 exhibits a potency of 290 ± 80 nM at rat mGlu4 and induces an 18.1 ± 1.7-fold left shift of the glutamate concentration-response curve. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mGluR | ||
Structure
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