BMS-986020
| CAS No. | 1257213-50-5 | Cat. No. | BCP19107 |
| Name | BMS-986020 | ||
| Synonyms | BMS 986020;BMS986020; AP-3152 free acid; AM152; AM 152; AM-152; | ||
| Formula | C29H26N2O5 | M. Wt | 482.53 |
| Description | BMS-986020, also known as AM152 , is a potent and selective LPA1 antagonist. BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions like cell proliferation, platelet aggregation, smooth muscle contraction, chemotaxis, and tumor cell invasion, among others. | ||
| Pathways | GPCR/G Protein | ||
| Targets | S1P Receptor | ||
Structure
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