Sophoflavescenol

  • Chemical Properties
CAS No. 216450-65-6 Cat. No. BCP24815
Name Sophoflavescenol
Synonyms
Formula C21H20O5 M. Wt 368.38
  • Biological Activity
Description Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 µM, 0.17 µM, 17.89 µg/mL, 10.98 µM, 8.37 µM and 8.21 µM, respectively.
Pathways Protease/Metabolic Enzyme Neuro Signaling Pathway 
Targets Phosphodiesterase/PDE Beta secretase AChE 

Structure

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