CEP-28122 monomesilate hydrochloride salt

  • Chemical Properties
CAS No. 1354545-57-5 Cat. No. BCP24832
Name CEP-28122 monomesilate hydrochloride salt
Synonyms CEP 28122 monomesilate hydrochloride salt;CEP28122 monomesilate hydrochloride salt;
Formula C29H40Cl2N6O6S M. Wt 671.64
  • Biological Activity
Description CEP-28122 is a highly potent and selective orally active ALK inhibitor with a favorable pharmaceutical and pharmacokinetic profile and robust and selective pharmacologic efficacy against ALK-positive human cancer cells and tumor xenograft models in mice. Anaplastic lymphoma kinase (ALK) is constitutively activated in a number of human cancer types due to chromosomal translocations, point mutations, and gene amplification and has emerged as an excellent molecular target for cancer therapy.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets ALK 

Structure

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