Avitinib maleate

  • Chemical Properties
CAS No. 1822357-78-7 Cat. No. BCP19161
Name Avitinib maleate
Synonyms Abivertinib maleate; AC0010MA; AC-0010MA; AC 0010MA; AC0010; AC-0010; AC 0010;
Formula C30H34FN7O8 M. Wt 639.6
  • Biological Activity
Description Avitinib maleate, the maleate salt form of avitinib, is a pyrrolopyrimidine-based, irreversible epidermal growth factor receptor (EGFR) mutant-selective inhibitor(IC50= 7.68 nM), with potential antineoplastic activity.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR 

Structure

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