Thiabendazole

  • Chemical Properties
CAS No. 148-79-8 Cat. No. BCP19179
Name Thiabendazole
Synonyms 2-(4-Thiazolyl)benzimidazole; Tiabendazole;
Formula C10H7N3S M. Wt 201.25
  • Biological Activity
Description Thiabendazole is a benzimidazole derivative with anthelminthic property. Although the mechanism of action has not been fully elucidated, thiabendazole inhibits the helminth-specific mitochondrial enzyme fumarate reductase, thereby inhibiting the citric acid cycle, mitochondrial respiration and subsequent production of ATP, ultimately leading to helminth's death. In addition, it has been suggested that thiabendazole may lead to inhibition of microtubule polymerization by binding to beta-tubulin and has an overt ovicidal effect with regard to some trichostrongylids.
Pathways Others Pathway 
Targets Others 

Structure

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