GDC-0853
| CAS No. | 1434048-34-6 | Cat. No. | BCP19175 |
| Name | GDC-0853 | ||
| Synonyms | GDC0853;GDC 0853;Fenebrutinib; RG-7845; RG7845; RG 7845; | ||
| Formula | C37H44N8O4 | M. Wt | 664.8 |
| Description | GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, which leads to the inhibition of the growth of malignant B-cells that overexpress BTK. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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