CPI-1205
| CAS No. | 1621862-70-1 | Cat. No. | BCP19174 |
| Name | CPI-1205 | ||
| Synonyms | CPI 1205;CPI1205; | ||
| Formula | C27H33F3N4O3 | M. Wt | 518.57 |
| Description | CPI-1205 shows excellent oral bioavailability. It was well-tolerated for repeat dosing as demonstrated by the absence of significant body weight loss. CPI-1205 shows relatively high clearance in both rats and dogs (3.19 L/h/kg and 1.41 L/h/kg, respectively) but demonstrates good oral bioavailability in both species(44.6% F in rats and 46.2% F in dogs). CPI-1205 was well-tolerated in the 28-day GLP toxicology studies, and any findings were reversible over the recovery period. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Methyltransferase | ||
Structure
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