YM-58483
| CAS No. | 223499-30-7 | Cat. No. | BCP19298 |
| Name | YM-58483 | ||
| Synonyms | BTP2;YM 58483;YM58483;CRAC Channel Inhibitor, BTP2;BTP-2;BTP 2; | ||
| Formula | C15H9F6N5OS | M. Wt | 421.32 |
| Description | YM-58483 is a calcium release-activated calcium (CRAC) channel inhibitor. YM 58483 suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM), cytokine production and proliferation of T cells in vitro. YM 58483 exhibits immuno-modulatory and anti-inflammatory activity. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CRAC Channel | ||
Structure
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