Pipequaline

  • Chemical Properties
CAS No. 77472-98-1 Cat. No. BCP19330
Name Pipequaline
Synonyms PK-8165;PK8165;PK 8165;RP45319;RP 45319;RP-45319;
Formula C22H24N2 M. Wt 316.45
  • Biological Activity
Description Pipequaline, also known as PK-8165, is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic. Pipequaline acts as a non-selective GABAA receptor partial agonist. While its profile of anxiolytic effects without sedation would appear to have potential medical applications, pipequaline has never been developed for medical use and is currently only used in scientific research.
Pathways Ion Channel/Membrane Transporter 
Targets GABA Receptor 

Structure

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