Rapastinel acetate
| CAS号 | 491872-39-0 | 货号 | BCP24900 |
| 中文名 | Rapastinel acetate | ||
| 英文名 | Rapastinel acetate | ||
| 中文别名 | |||
| 英文别名 | GLYX-13; GLYX 13; GLYX13; BV-102; BV102; BV 102; TPPT-amide; | ||
| 分子式 | C20H35N5O8 | 分子量 | 473.52 |
| 生物活性 | Rapastinel is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-orally active) amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%). | ||
| 上下游产品 | 1435786-04-1（Rapastinel Trifluoroacetate） | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | mGluR | ||
结构式
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