CNDAC HCl salt
| CAS号 | 134665-72-8 | 货号 | BCP19489 |
| 中文名 | CNDAC HCl salt | ||
| 英文名 | CNDAC HCl salt | ||
| 中文别名 | |||
| 英文别名 | TAS109; TAS-109; TAS 109; DFP-10917; DFP 10917; DFP10917; CNDAC; | ||
| 分子式 | C10H13ClN4O4 | 分子量 | 288.69 |
| 生物活性 | CNDAC, also known as DFP-10917 and TAS-109 , is an analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | Antimetabolite | ||
结构式
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