Valbenazine

  • Chemical Properties
CAS No. 1025504-45-3 Cat. No. BCP19498
Name Valbenazine
Synonyms NBI 98854;NBI-98854;NBI98854; MT-5199; MT 5199; MT5199;
Formula C24H38N2O4 M. Wt 418.57
  • Biological Activity
Description Valbenazine, also known as NBI-98854 and MT-5199, is a potent and selective VMAT2 inhibitor. NBI-98854 is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. NBI-98854 is promising agent for the treatment of tardive dyskinesia.NBI-98854 significantly improved tardive dyskinesia and was well tolerated in patients. These results support the phase 3 clinical trials of NBI-98854 now underway.
Pathways Ion Channel/Membrane Transporter 
Targets Monoamine Transporter 

Structure

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