EPZ011989 trifluoroacetate
CAS No. | 1598383-41-5 | Cat. No. | BCP24955 |
Name | EPZ011989 trifluoroacetate | ||
Synonyms | EPZ-011989 trifluoroacetate;EPZ 011989 trifluoroacetate; | ||
Formula | C37H52F3N5O6 | M. Wt | 719.83 |
Description | EPZ011989 trifluoroacetate is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase. | ||
Pathways | Epigenetics | ||
Targets | Histone Methyltransferase Epigenetic Reader Domain |
Structure
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