EPZ011989 trifluoroacetate

  • Chemical Properties
CAS No. 1598383-41-5 Cat. No. BCP24955
Name EPZ011989 trifluoroacetate
Synonyms EPZ-011989 trifluoroacetate;EPZ 011989 trifluoroacetate;
Formula C37H52F3N5O6 M. Wt 719.83
  • Biological Activity
Description EPZ011989 trifluoroacetate is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
Pathways Epigenetics 
Targets Histone Methyltransferase Epigenetic Reader Domain 

Structure

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