MK1064

  • Chemical Properties
CAS No. 1207253-08-4 Cat. No. BCP19608
Name MK1064
Synonyms MK-1064;MK 1064;
Formula C24H20ClN5O3 M. Wt 461.9
  • Biological Activity
Description In vivo: MK-1064 promotes sleep and increases both rapid eye movement (REM) and non-REM (NREM) sleep in rats at OX2R occupancies higher than the range observed for dual orexin receptor antagonists. MK-1064 increases NREM and REM sleep in dogs without inducing cataplexy. The reference for animal administration is 30 mg/kg.
Pathways GPCR/G Protein 
Targets OX Receptor 

Structure

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