MK1064
CAS No. | 1207253-08-4 | Cat. No. | BCP19608 |
Name | MK1064 | ||
Synonyms | MK-1064;MK 1064; | ||
Formula | C24H20ClN5O3 | M. Wt | 461.9 |
Description | In vivo: MK-1064 promotes sleep and increases both rapid eye movement (REM) and non-REM (NREM) sleep in rats at OX2R occupancies higher than the range observed for dual orexin receptor antagonists. MK-1064 increases NREM and REM sleep in dogs without inducing cataplexy. The reference for animal administration is 30 mg/kg. | ||
Pathways | GPCR/G Protein | ||
Targets | OX Receptor |
Structure
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