Acebilustat

  • Chemical Properties
CAS No. 943764-99-6 Cat. No. BCP19611
Name Acebilustat
Synonyms
Formula C29H27N3O4 M. Wt 481.54
  • Biological Activity
Description Acebilustat is an antiinflammatory drug in development for the treatment of CF and other diseases. It is a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a potent chemoattractant and activator of inflammatory immune cells including neutrophils.
Pathways GPCR/G Protein 
Targets Leukotriene Receptor 

Structure

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